Diuretics - madhiragi anonyanya kubata mainyo uye anobatsira pakukurumidza kubviswa kwemuti kubva mumuviri. Chaizvoizvo, dzinoshandiswa kurongedza kuenzana kwe-acid-base yemuviri, kurapa kwepfungwa dzemwoyo, zvirwere zvekuvhenekera, kutyisa nehutu hwezvinhu, nezvimwewo. Mune mamiriro akasiyana-siyana, mamwe marudzi e diuretics anoratidzwa, iyo nzira yekuita iyo inobva pane zvakasiyana-siyana. Ngationei pane zviitiko zvipi kushandiswa kwe thiazide diuretics kunorumbidzwa, uyewo maitiro avanoita uye mishonga inoratidzwa.
Iyo nzira yekuita kwe thiazide diuretics
Iyi mishonga inoshandiswa mishonga yepakati yakasimba simba, iyo inogadziriswa inenge inenge maawa maviri nemaviri mushure mokutungamira uye inopedza maawa gumi nemaviri. Thiazide diuretics inoshandisa distal renal tubules, iyo inoratidzwa nemigumisiro mikuru inotevera:
- kudzvinyirirwa kwekudzokazve kwekaini yakasvibiswa uye chlorine;
- kuwedzera mune excretion ye potassium uye ion magnesium;
- kuderera muzvinyorwa zve calcium ions mumuguta;
- kuderera mukusunungurwa kweUric acid, nezvimwewo.
Muzhinji, thiazide diuretics inorayirwa kuti:
- edema inofambisa kuenzanisa mwoyo kusakundikana, chiropa uye zvinetso zvephenyo;
- ane chirwere chisingaperi chisinganzwisisiki kuderedza kushandiswa;
- chirwere cheshuga insipidus ;
- glaucoma;
- idiopathic calciuria.
Dzimwe nguva mishonga iyi inosanganiswa ne loop diuretics, iyo inobatsira kuderedza madhara-ane chokuita nemigumisiro inoratidzika yemhando imwe yemhando idzi dzemishonga.
Rwendo rweTiazide Diuretics
Nhamba ye diuretics yehetide series inomiririrwa nekugadzirira nemiti yakawanda inoshandiswa, izvo zvakanyanya ndezvi:
- hydrochlorothiazide;
- indapamide ;
- clopamid;
- Chlorthalidone.