Thyreperoxidase iine enzyme inokonzerwa nemasero emakemikari anobatanidza muhutano hwe thyroxine uye triiodothyronine hormones uye anoshumira kuita chimiro chinoshanda cheIodine mumuviri. Zvirwere zvehutachiita ku thyroid hyperoxidase (masimba anokwana microsomal thyreperoxidase) ari autoantibodies kune iyi enzyme, iyo inoumbwa apo maitiro ezvirwere zvezvirwere zvezvirwere zvisinganzwisisiki maseroji echinhu sechinhu chekunze.
Kuongororwa kwezvirwere kune utachiona peroxidase
Kutakura kuongororwa kwezvirwere kune utachiona peroxidase kunobvumira kuburitsa zvakasiyana-siyana zvinokonzera utachiona. Kuonekwa kwezvinhu izvi muropa kunotungamirira kuderera kwekugadzirwa kwehomoni uye kuparadzwa kwemasero echitendero, izvo zvinokonzera dzimwe zvirwere. Zvirwere zvehutachiona hwetroroid peroxidase zvinogona kuwanikwa mune zvishoma muvanhu vane utano (kusvika kusvika 20% pakati pevakadzi). Kukosha kwechimiro chezvinyorwa zvemasimba kunotora thyreperoxidase muropa kunobva pane imwe nzira yekuedza inoshandiswa, iyo inoratidzirwa nehutano hwakanaka hwekunzwisisika uye nemiganhu yezvinyorwa zvinowanikwa.
Zvikonzero zvekuwedzera huwandu hwezvirwere zvinopesana ne thyreperoxidase:
- Kakawanda kudarika kwechigarire kunogona kusanganiswa nehutano hwakawanda hwehutachiona hwehutachiona, uyewo zvirwere zvakasiyana-siyana zvemotokari (systemic lupus erythematosus, rheumatoid arthritis, systemic autoimmune vasculitis, chirwere cheshuga, kenza yekameti, nezvimwewo).
- Kana zvipembenene zvinoshandiswa ne thyreperoxidase zvakanyanya kuwedzerwa, zvinowanzoratidza chirwere chetachiona chemotokari (Hashimoto's thyroiditis, inopararira toxic goiter).
- Kuwedzera kwehuwandu hwemishonga inorwisa thyreperoxidase mumukadzi panguva yekuzvitakura kunogona kuratidza hyperthyroidism mune mwana anouya.
- Kana uchitarisa hutachiona hwehutachiona hwehutachiona peroxidase panguva yekurapa, kuongorora kubudirira kwayo, kukwirira kwepamusoro kunoratidza kuwedzera kwezvirwere zviripo kana kusakwanira kwakakwana kwerapi (kana, zvakasiyana, zvirwere zvetachiona peroxidase zvinoderedzwa, izvi zvinoratidza kubudirira kwerapi).
Zviratidzo nehupamhi hwehutachiona hunotapukira kuhutachiona peroxidase
Kana zviratidzo zvehuwandu hwemasikirini eti thyreperoxidase muropa huwedzerwa, ipapo kuvapo kwezviratidzo zvakadaro kunogoneka:
- kuputsika uye kurasikirwa kwevhudzi ;
- ganda rakaoma;
- kuzvimba;
- kurasikirwa kwekunzwa;
- change of voice;
- kuwedzera kutuka;
- moyo palpitations;
- kushushikana kwehope, nezvimwewo.
Migumisiro yekuwedzera mishonga inorwisa utachiona peroxidase
Kuwedzera kwemaitiro ekurwisa zvirwere kune utachiona peroxidase - chiratidzo pamusoro pokukundikana kwemaununiti mumuviri. Somugumisiro, musishuloskeletal, mwoyo, mushu, zvirwere zvekudya zvinogona kuchinjwa. Vakadzi vanogona kutambura nekuberekwa, kureva kuti, kupfuura chirevo chezvakagadzirirwa zvezvirwere kune utachiona peroxidase chinhu chinokonzera kukanganisa kubvisa pamuviri.
Kurapa nehuwandu hwehutachiona hwehutachiona hwetroroid pasexidase
Kana uwandu hwemasikirini eti thyreperoxidase huwedzerwa zvikuru, mimwe miedzo inotarisirwa kusati yatapwa:
- Nhamba ye thyroid-stimulating hormone ;
- thyroxine level;
- nhamba ye triiodothyronine;
- muzinga wekusununguka utachiona hwehomoni.
Uyewo zvinotarisirwa kuitisa ultrasound yejeremusi gland. Maererano nemigumisiro yakawanikwa, kuongorora kwakarurama uye kugadzwa kwekambani yekurapa kunogoneka. Sezvo mutemo, kurapwa kwemishonga inokurudzirwa. Mune ramangwana, kuongororwa nekuongororwa kunotarisirwa kunoda kushandura huwandu hwemhomoni uye ma antibodies kune utachiona peroxidase.