Gilbert's syndrome - zviratidzo

Gilbert's syndrome (Gilbert's disease, kwete mhuri yehemolytic jaundice, chirwere chemaitiro chisina kuchena, chirongwa chebumbiro rezvemutemo) chirwere chinokonzerwa nemararamiro, chinokonzerwa nekuchinja kwegene rinokonzera kubvisa bilirubin muropa. Chirwere chacho chakatumidzwa zita reFrench gastroenterologist Augustine Nicolas Gilbert, uyo akatanga kuritsanangura muna 1901. Chirwere cheGilbert chinowanzozviratidza senhare yakakwirira yebilirubin muropa, jaundice nezvimwe zviratidzo zvisingaoneki uye hazvirevi kurapwa kwakakurumidza.

Zviratidzo zveGilbert's Syndrome

Zviratidzo zvikuru zvechirwere ichi zvinosanganisira zvinotevera:

1. Jaundice, paakatanga kutarisa icteric kudonhedzera kwechiso cheziso (kubva zvisinganzwisisiki kutaura). Muzviitiko zvisingawanzoitiki, pangave nekudengenyeka kweganda mu nasolabial triangle, matende, mapfumo.
2. Kushungurudzika muhana yakanaka ye hypochondrium, pane dzimwe nguva, pangave kuwedzera kuwedzera kwechiropa chiyero.
3. Kazhinji kushaya simba uye kuneta.
4. Mune zvimwe zviitiko, kushungurudzwa, kushungurudzwa, kugadzikana kwechigaro, kusawirirana kune zvimwe zvokudya zvinogona kuitika.

Chikonzero cheGilbert's syndrome ndechokushayikwa muropa yechinyimusi chaiyo (glucuronyltransferase), iyo inokonzera kushandiswa kwebilirubin. Somugumisiro, chete kusvika pamakumi matatu kubva pane makumi matatu kubva muzana yeiyo bile pigment inoderedzwa mumuviri, uye kuwedzera kunowedzera muropa, zvichiita kuti zviratidzo zvinowanzoitika zvechirwere ichi - jaundice.

Kuongororwa kweGilbert's Syndrome

Kuongororwa kweGilbert's syndrome kunowanzoenderana nekuedzwa kweropa:

1. Zvose bilirubin muGilbert's syndrome yakabva kune 21 kusvika ku 51 μmol / l, asi inogona kuwedzera kusvika ku 85-140 μmol / l pasi pesimba rekuita muviri kana kuti nezvimwe zvirwere.
2. Sample ne nzara. Inotsanangura kuongororwa (kwete kazhinji) kuGilbert's syndrome. Mukurwisana kwekutsanya kwekutsanya kana kuchengetedzwa mukati mezuva remazuva maviri e-calorie diet, bilirubin muropa rinokura kubva 50-100%. Mitezo yebilirubin inoitwa mudumbu risina chinhu musati maedzwa, uye shure kwemazuva maviri.
3. Sample ne phenobarbital. Paunotora phenobarbital, uwandu hwebilirubin muropa rinodonha zvakanyanya.

Nzira yekurarama nayo naGilbert's syndrome?

Chirwere chacho pachacho hachina kuonekwa sengozi uye hachiwanzodi kurapwa zvakananga. Kunyange zvazvo nhamba yakakwirira yebilirubin muropa inopfuurira muhupenyu hwose, asi hutano hwayo hahuna kusvika pachiyero chinotyisa. Migumisiro yechiratidzo cheGilbert chinowanzowedzera kune kuratidzwa kwekunze uye kusagadzikana zvishoma, naizvozvo, kunze kwekudya, kurapa kunoshandisa chete kushandisa hepatoprotectors kunatsiridza chiropa basa. Uyewo (mune zvisinganzwisisiki, chirwere chakanyanya jaundice) kutora zvinodhaka zvinobatsira kubvisa pigment yakawanda kubva mumuviri.

Mukuwedzera, zviratidzo zvechirwere hazvisi zvachose uye nguva yakawanda inogona kunge isingazivikanwi, inowedzera nokuwedzera simba, kunyanya kudhakwa, nzara, kutonhora.

Chinhu chimwe chete chinogona kuva nengozi Gilbert's syndrome - muzviitiko zvisingawanzoitiki, kana hurumende isingarumbidzwi uye kushaiwa kwekudya, inobatsira kukura kwekuvhiringidza kwebazi rebhaariary uye cholelithiasis .

Uye zvinofanira kurangarirwa kuti chirwere ichi chinowanikwa, saka kana pane nhoroondo yemumwe wevabereki, zvinokurudzirwa kutarisa geneticist vasati vatanga kubata pamuviri.