Squamous cell carcinoma - sei kuziva marudzi ose ezvirwere?

Pamusana pezvikonzero zvisingazivikanwi, epithelial tishues eganda uye mucous membrane dzimwe nguva inopera muhutachiona husina kunaka. Matumbu akadaro anowanzoonekwa kuvanhu veCaucasian yemazera ekukwegura (mushure memakore makumi matanhatu nemazana matanhatu nemashanu). Kana pane chimiro chekuberekwa kwemazwi, vanoonekwa kuti vari vana.

Squamous cell carcinoma - kuongorora

Iyo inorondedzerwa chirwere inofambira mberi nokukurumidza uye metastasizes kunyange mumatanho ekutanga ekugadzirwa, saka zvakakosha kuona chirwere mumungu uye pakarepo unotanga kurapwa. Kuongororwa kunoitwa pamusana pekuongororwa kwemurwere uye anamnesis nenotsanangudzo yakazara yezviratidzo zviripo. Rudzi rwakawandisa rwekenza ndeye squamous cell carcinoma, iyo inoratidzika seganda guru. Izvo zvakaoma kusiyanisa kubva kubhenji kukura, nokuti iyo inokwanisa kusunungura metastases kune lymph nodes dziri pedyo uye nhengo.

Kuratidza kacoma uye mamwe maitiro ekenza dzinoverengeka dzidzo dzinoitwa:

• Kuongororwa kwezvisikwa zvehupenyu (urini, ropa);
• biopsy;
• oncological panel;
• magnetic resonance uye computed tomography ;
• radiography;
• ultrasound diagnostics.

Yakanyatsosiyaniswa squamous cell carcinoma

Mimwe mhando yemakumbo muurongwa uye sarudzo inenge yakangofanana nemasikirwo ane hutano, pachishandiswa zvavakakura. Mhando dzakadaro dzemasikirwo emasikirini dzinonzi dzakasiyana kwazvo. Izvi zvinokonzera chitunha chemaoko zvakaoma kuona, saka kuongororwa kweropa kwakananga kwakagadzirirwa kutarisa zvinhu zvakananga zvinongorora matumire anowanikwa. Penguva yekudzidza, squamous cell carcinoma antigen inotsvakwa muhupenyu hwehupenyu. Maabara ekurapa anoratidza chiratidzo ichi sechidimbu SCC kana SCCA.

Zvinyatsosiyanisa squamous cell carcinoma

Nzira yakarongeka yeooplasms inosanganisira masero akave akashandurwa. Matumbo akadaro akareruka kuongororwa nekuda kwechimiro chavo uye kusadzora kutadzaniswa. Zvichienzaniswa nemukenza zvinokonzerawo SCC squamous cell carcinoma antigen, asi mukuwedzera kuwanda. Kunyanya kuiswa kwemavara kunopa kukurumidza kuonekwa kwehutachiona uye kutanga kwakakodzera kwerapi.

Low-differentiated squamous cell carcinoma

Ichi ndicho chiremera chinonyanya kushandiswa chekuongororwa. Icho chimiro chakasiyana kwazvo nehutano. Low-differentiated squamous cell carcinoma inosanganisira mutated, maitiro asina kukwana ane makumbo asina kufanana. Muchigadzirwa chayo, zvipembenene zvakajairika hazvisipo zvachose, naizvozvo inonzi neoplasm inokurumidza kubudiswa nenzira yebiopsy kana dzimwe nzira yekuongorora.

Chirwere chinokonzera kuuraya kenza

Kana sero rechirwere rinosangana nekuchinja, rinotanga kuparadzanisa zvese, nekugadzira clones risina basa. Kana squamous cell carcinoma inokura ne cornification, dzimwe mishonga dzinotanga kufa. Kutorwa kwemasero e clone kurasikirwa kukwanisa kugovana nekuunganidza keratin. Izvi zvinoratidzika sechitarisiko pa-neoplasm ye-crusts yakareba yemajagi.

Chirwere chisina kukodzera

Mune mamiriro ezvinhu akarondedzerwa, kusadzora kukanganisa kwechitokisi mumutambo wekare kunowanikwawo, asi ma clones haafi. Caramoma isingabatsiri inofungidzirwa inonzi inonyanya kuipa yekenza yakadaro, nokuti kukura kwayo kunowedzera nguva dzose. Maitiro echipatholo akashandura masero haaunganidzi keratin, asi nguva yose iyo inokonzera uye inotanga metastases kune lymph nodes uye nhengo dzomunharaunda.

Squamous cell carcinoma yeganda

Ruzhinji (inenge 90%) yezviitiko zvekuongororwa mumubvunzo zvinosanganiswa muboka rezvikwata zvinowedzera. Neoplasms inonyanya kuonekwa pazvikamu zvakasununguka zvemuviri unobudiswa nemirairo ye ultraviolet (chiso, mutsi nemaoko). Squamous cell carcinoma - zviratidzo:

• kukura kana kuchinja muhumwe, ruvara rwe birthmark , warts;
• kusuruvara muropation yemhutu;
• itching;
• nguva yekupisa nguva;
• kubwinya kwepamusoro penharaunda yakakanganiswa;
• kuzvimba kweganda rakapoteredza;
• kukanganisa kunzwisisika munzvimbo yekukuvara.

Squamous cell carcinoma yemukati

Imwe nzvimbo yekukura kwechiremera ichi inharaunda yekushanduka kwakanaka kwe multilayer epithelium mu cylindrical epithelium. Gynecologists inoratidza kuti squamous cell carcinoma yemukati mutsva inokurwisana nechepamusoro pepillomavirus inofambira mberi yevanhu. Iyi hutachiona muhupenyu husingaperi yakawanikwa muna 75% yevarwere vane chirwere chinorondedzerwa chirwere. Chirwere chechirwere chechibereki chisina kukwana chinowanzozivikanwa, nokuti sarudzo ye multilayer epithelium inoisa masero mune cloning isingadzorwi. Zviratidzo zvinoshamisa hazvina maturo:

• kubuda ropa pakarepo mushure mekushamwaridzana;
• kugara nekurwadziwa mupfungwa munzvimbo ye pubic;
• kukanganisa kwekuzvidzivirira;
• kuora ropa kunze kwekuenda kumwedzi;
• kurwadziwa panguva yepabonde;
• matambudziko nekudhonza.

Squamous cell carcinoma yemapapu

Icho chinonzi neoplasm chinokura zvishoma nezvishoma pane mamwe maitiro echirwere uye nguva refu haifaniri kutevera chero zviratidzo. Squamous cell carcinoma yemapapu ine ruvara rwemhepo, inowanzokura mumudzi wechipfu (anenge 70% ematambudziko), dzimwe nguva chironda chinowanikwa mune ruvara rwebhononi. Sezvo uwandu hwacho huchiwedzera, hutachiona hunokonzera kenza hunovhiringidza (kudzivirira) kwehutano hwekupemha. Mukufananidza, inoumba matanda ane necrosis mukati uye inobvumira mitambo yakawanda.

Pulmonary squamous cell carcinoma ine kliniki yakadaro:

• kuora kwenguva refu kwenguva refu;
• expectoration yeropa;
• kugara nekubatana kwepneumonia nedzimwe zvirwere zvinopisa;
• manzwiro ekushaikwa kwemhepo;
• kukurumidza kufema.

Squamous cell carcinoma yelarynx

Rudzi rwakarondedzerwa rwechirwere chinouraya chinogona kuva chemarudzi maviri:

1. Infiltrative-ulcerative kana endophytic squamous cell carcinoma yemarara - kutanga kemukati kadiki inowanikwa pane epithelium, iyo inopedzisira ichisa. Mushure mechinguva, chidimbu chakavakwa nemigumisiro yakafanana yakatanga zvakare. Zvironda zvinowedzera nekubatana, zvichiumba nzvimbo yakawanda yekukuvara.
2. Tumor squamous cell carcinoma (exophytic carcinoma). Ikoplasm ine maitiro edzimba huru ine zvishoma zvishoma. Iyo inowedzera nokukurumidza muhupamhi, inogona kufukidzwa ne yellow yellow masero, zviyero uye zvigadzirwa zve warty.

Unhu hunosanganisira:

• hoarseness of voice;
• aphonia;
• kupfupika kwemhepo;
• akadzikama;
• manzwiro ekuvapo kwechinhu chekunze mumutsipa (gumbo);
• hemoptysis.

Squamous cell carcinoma yeeophagus

Ngozi yekuitika kwechirwere ichi chakaipa chinowedzera nekuwedzera kwegastroesophageal reflux chirwere . Mukurwisana kwemashure ekukanda jisi rinokonzera mukati mechipu, mhando duku yemakumbo pamadziro ayo, izvo zvishoma nezvishoma zvinosvika pakukura kukuru. Nemhaka yezviratidzo zvisingaoneki, kurapwa kwe squamous cell carcinoma kazhinji kunotanga kakatova mumatanho ekupedzisira. Zviratidzo Zvinozivikanwa:

• marwadzo munharaunda yekutambudza yemunhu anonyanyisa;
• dysphagia (kunetseka kumedza);
• kurutsa ropa;
• kunhuhwirira kunofadza pane kubuda, kunyanya kana bundu racho riri necrotic kana utachiona hunobata;
• kubata nezvidimbu zvekudya;
• kuchema;
• ropa inowanika mumasese.

Squamous cell carcinoma ye rectum

Chirwere cheavo chakatsanangurwa kunowanikwa kuburikidza nemakiriniki epiriniki zvakafanana zvakafanana nehemorrhoids, saka varwere vanodzokera kune oncologist vatova kumagumo ekupedzisira kwehutano hwehutano. Carcinoma ye rectum inowanzobatanidzwa nedzimwe nhengo dzekukuvadza - kuputika mune anus, kuvhiringidzika uye thrombosis yemakwenzi. Zviratidzo zvakananga:

• manzwiro emuviri wekunze mune rectum;
• kuchenesa mukati kana pedyo ne anus;
• kurwadziwa mu anus;
• matambudziko ane defecation, kunyanya kuvhiringidzika kana kushandiswa kwavo nehuvha;
• "Makwai ane zviyo" - chigaro mune zviduku zviduku zvakaoma;
• Kuvhara marwadzo mudumbu rezasi kuruboshwe;
• kubudiswa kweropa mushure mokubviswa kwemukati, chirwere chehupenyu chinopenya tsvuku, chinogona kuvhara nyaya yefecal;
• kusuruvara mukugara uye kufamba.

Squamous cell carcinoma yerurimi

Kune ma 3 matomical mhando yemaronda akadaro:

1. Infiltrative. Iko kukura kunoratidzika sechisimbiso, zvakafanana mukukwirira kumatumbu ane utano. Chirwere chinokonzera masero chinokonzera chirwere chinotapukira, chinokonzera mitsara uye chinokonzera kurwadziwa kwakanyanya chirwere munguva yekufamba uye kutarisa kwemirimi.
2. Ulcerative. Panhengo iyo panotanga kudengenyeka kuduku, izvo zvishoma nezvishoma kunowedzera uye kuwedzera.
3. Papillary. Squamous cell carcinoma inonyatsooneka yakajeka, tumarara ine mufananidzo webhora, inonyatsofamba ichikwira kumusoro kwepamusoro epithelium yakazara. Mhando iyi yeooplasm inokura zvishoma kudarika zvataurwa pamusoro apa.

Kanzira yerurimi - zviratidzo:

• kurwadziwa munyaya yemuromo;
• kwete-kuporesa ulcers pamusoro;
• ichipisa mumuromo;
• itching;
• putrefactive kufema;
• kubuda ropa;
• kuoma kuzarura muromo uye kudya;
• copious salivation;
• kurasikirwa nokurema;
• kuzvimba kana kuzvimba kwechiso, mutsipa;
• kusunungura nekurasikirwa kwemeno;
• kubuda ropa;
• kuvapo kwezvisimbiso kana mavara mumuromo.