Chirwere chinotapira chinowanikwa pane chimwe chezvinyorwa zvinonzi adrenal kana mune dzimwe nhengo dzenheyo dzenheyo dzinonzi pheochromocytoma - zviratidzo zvechirwere ichi zvinopupurira basa reHommonal ye-neoplasm. Inoumbwa nemasero e-chromaffin tissue uye brain brain. Zvirwere zvinosuruvarisa zvemhando iyi hazvishamisi, mumatambudziko gumi chete chete.
Pheochromocytoma - zvinokonzera
Hazvizivikanwi nei chirwere ichi chichikura. Pane kunetseka kuti neoplasm inoratidzika semugumisiro weiyo genetic mutations.
Kazhinji kacho chirwere chinokanganisa vanhu muhukuru, kubva pamakore makumi mashanu nemashanu kusvika makumi mashanu, kunyanya vakadzi. Kazhinji, tumarara inokura muvana, uye kakawanda inowanikwa kune vakomana.
Zvinonyadzisa pheochromocytoma zvinowanzobatanidzwa nedzimwe mhando dzekenza (utachiona, utumbo, mucous membrane), asi metastases haisi maitiro.
Zviratidzo zve pheochromocytoma
Symptomatology zvakananga kunobva pane nzvimbo yemarara, sezvo chiremara chedrenal gland inobereka 2 marudzi emahomoni: adrenaline uye norepinephrine. Mune dzimwe nguva, inogadzira norepinephrine chete. Saizvozvowo, mhinduro ye pheochromocytoma ichave yakanyanya kuonekwa neyo nzvimbo yepamusoro.
Mukuwedzera, zviratidzo zvakasiyana nemhando dzinozivikanwa dzechirwere, izvo zvinorondedzerwa maererano nekliniki yekuti:
- paroxysmal;
- nguva dzose;
- kusanganiswa.
Paroxysmal pheochromocytoma - zviratidzo:
- the classical triad of Carney (moyo palpitations, kuwedzera kutuka, musoro wemusoro);
- inopinza uye kamwe-kamwe kuwedzera kweropa rekuyeresa zvinoratidza 300 mm Hg. Art. uyezve;
- pallor;
- chinhu chisinganzwisisi chekutya;
- chizoro;
- kurwadziwa mukati mamuviri uye shure kwe sternum;
- kupfupika kwemhepo;
- nausea;
- polyuria;
- kuonekwa kusakanganisika;
- kuwedzera mukushisa;
- kurutsa.
Nokuti chimiro chenguva dzose chechirwere chinoratidzirwa nekuwedzera kunowedzera kuwedzera kwezvinomanikidzwa uye zviratidzo zvakafanana neyendo yehosha yehutachiona.
Mixed type ye neoplasm inokonzera mhirizhonga yehutachiona - ne pheochromocytoma inogona kukonzera kuora kukuru kwetina mu retina yeziso, chirongwa chemapemmata kana chirwere.
Pheochromocytoma - diagnostic
Kuongororwa kunoitwa mushure mekuverengeka kweongororo yekuongorora:
- chidzidzo cheropa chekuchengetedzwa kwekatecholamines, kuvapo kweukoukocytosis, kuwedzera ESR, hyperglycemia, erythrocytosis, eosonophilia;
- urine kuongorora kwekuzivikanwa kwe cylindruria, proteinuria, glucosuria, excretion ya vanillylmandelic acid;
- maitiro anoshanda ne histamine uye reginal.
Zvimwe zvinowanikwa zvinogona kuwanikwa kuburikidza ne ultrasound yeadrenal glands , computed tomography, aortography, scintigraphy.
Inofanira kuonekwa kuti pheochromocytoma ine nguva yekuwana nguva yakakwana yekuona chirwere ichi munguva uye kutanga utachiona. Nokudaro, munhu wese anotambudzika nehuwandu hwehutachiona anoda kuongororwa kuchipatara kuti asabvisa chiremera chiri mubvunzo sechikonzero chekuwedzerwa kweropa.
Pheochromocytoma - zvinetso uye kufungidzira
Zvizhinji zvemigumisiro yakaipa inokura mushure mematambudziko:
- myocardial infarction;
- kupararira kusina kunaka kweuropi;
- pulmonary edema ;
- mwoyo kukanganisa.
Mukushayikwa kwezvinodiwa zvekurapa, varwere, chaizvoizvo, vanoparara.
Kurapa panguva yakakodzera uye kubviswa kushandiswa kweepheochromocytoma kunobvumira kuwana maitiro akanaka, kunyanya kana bundu racho risina kuipa uye hapana maitiro. Sezvakaratidzwa zvinoratidza, kudzokera kunowanikwa chete mu5-10% yematambudziko, uye zvigadziriswa zviitiko zvakanyatsogadziriswa nekubatsirwa kwemishonga.