Myasthenia gravis ndechimwe chezvirwere izvi zvinopesana, zvinowanzobatwa nevanhu vari vaduku. Zvinyorwa kubva mumutauro wechiGiriki zita iri rinoshandurwa se "musimba usina simba", rinotsanangura muchidimbu chiratidzo chikuru. Nenzira, isu hatisi kutaura pamusoro pezvakagara zvichitambura musimba, izvo vanhu vanowanikwa mushure mekuita. Pano mubvunzo unonyanya kuoma - chirwere chinokonzera skeletal musculature, kunyanya musoro nemutsipa.
Zvichemo uye Chokwadi
Kwekutanga nguva myasthenia gravis chirwere inorondedzerwa muzvinyorwa zvemazana zana remakore rechi17, uye muzana remakore rechi19 yakawana zita rechiremera. Kurapa kwakakwana uye kwakagadzirwa kwemishonga kwakashandiswa pakati pezana remakore rechi20, nekuvandudzwa kwezvinodhaka nguva dzose.
Myasthenia inorondedzerwa sechirwere chekudzivirira muviri, ndiko kuti, umo muviri wemunhu unotanga kushandiswa kwezvirwere zvezvirwere zvinotungamirirwa nemasero ake ane utano uye maviri uye nekuvandudzwa kwezvirwere zvinopisa.
Zvinonyanya kuzivikanwa kuti kazhinji nezviratidzo zve myasthenia gravis kune vakadzi, uye chirwere chinotanga kuzviratidza pacheche, kubvira pamakore makumi maviri kusvika makumi mana. Pano panewo mamiriro ekufambisa myasthenia gravis, iyo inofanirwa kuva nhaka. Chirwere chacho hachiwanzoitiki, chinenge 0.01% yehuwandu hwevanhu, asi vanachiremba vari kuona chiitiko kune dzimwe nguva zviitiko.
Zvinokonzera zvinokonzera uye nzira dzekuvandudza myasthenia gravis
Iyo nzira yekusimudzira myasthenia inobva pakuputsa kana kupedza zvakakwana kwebasa remasangano e-neuromuscular. Izvi zvinowanikwa pasi pesimba rezvirwere, izvo zvinobudiswa nemaune immune system (autoimmune reaction). Kazhinji, basa guru mubasa iri rinotaridza thymus gland - nhengo yehutachiona hwemunhu, umo chirwere chinorwara chinowanikwa. Nekuzvarwa kwechirwere ichi, vanachiremba vanoshevedza zvikonzero zvinokonzera kuchinja kwemajeni emapurotini, ayo anoshanda zvakananga mukuvakwa kwekubatana neuromuscular.
Vanachiremba vanotsanangura zvimwe zvinokanganisa zvinowedzera kuitika kwechirwere ichi:
- kushungurudzika kukuru;
- kazhinji kupemha hutachiona uye mamwe mazando;
- kuchinja kwekushanduka kwemamiriro okunze (nyika inopisa);
- mishonga yemishonga (mamwe antibiotics, beta-blockers, etc.).
Clinical manifestations
Myasthenia gravis inozviratidza muzviratidzo zvakasiyana-siyana, izvo zvinosanganiswa mumhando dzakasiyana-siyana:
- Ziso. Inowanzova danho rekutanga rechirwere. Inoratidzwa nekuderedza (ptosis) yemapusiki (kana imwe), strabismus, uye maonero maviri pane maziso, izvo zvinogona kuonekwa zviri zviviri mumapuranga akajeka uye akareba. Zviratidzo zvinowanzoshandura - kureva, zvinoshanduka zuva rose - dzinenge dzisina simba mangwanani kana kuti dzisipo, uye dzakaipa kusvika manheru.
- Bulbarnaya. Pano, mishonga yechiso nererynx inotanga kushungurudzwa, semugumisiro uyo murwere ane izwi remuromo, kusangana kwechiso chepiso kunowedzera, uye dysarthritic phenomena inooneka. Uyezve, kumedza nekucheka mabasa kunogona kuvhiringidzika, pakati pekudya. Kazhinji, mushure mekuzorora, mabasa anovandudzwa.
- Kushaya simba mumisungo yemakumbo nemutsipa. Varwere havaiti
vanogona kubata musoro wavo pamwe chete, ruzha rwakaputsika, zvakaoma kusimudza maoko kana kunyange kukwira kubva pachigaro. Munyaya iyi, kunyange mutoro muduku wenyama unowedzera zviratidzo zvechirwere.
Myasthenia gravis inogona kuzviratidzira zvose zviri mukati momufomu uye nzvimbo dzakawanda, iyo inonzi yakanyanya kuoma, sezvo inogona kukanganisa mabasa epumusoro wepumusoro. Chirwere chacho chine hupenyu hunofambira mberi, nechitarisiko chemashoko anogara kwenguva refu, asingapfuuri pazororo, pamwe nekutambudzika kwemaastenic, izvo zvinogona kutungamirira kurufu. Nokudaro, kana uine zviratidzo, unoda kuona chiremba.