Chimiro che bilirubin muropa

Chimwe chezvikamu zvikuru mukuongororwa kwezvirwere ndeye kuongorora kwehutachiwana hwehupenyu, umo huwandu hwezviratidzo huchigadziriswa, kusanganisira chimiro chebilirubin muropa. Funga kuti rudzi rwezvinhu zvakadini uye kuti runofanira kunge ruripo sei mukuongorora munhu ane utano.

Chii chinonzi bilirubin?

Bilirubin imwe yemadheremia eB bile, ane ruvara rwemutsvuku. Inoumbwa semugumisiro wekuparara kwezvikamu zveropa, kunyanya kubva ku hemoglobin, iyo inodzivirira masero matsvuku eropa panguva yekukuvara kwavo (kukuvadza) kana kukwegura kwepanyama. Hemoglobin inoputsika muheme uye globin maketani, izvo zvino zvinoshanduka kuva amino acids. Uye iyo, iyo inobatanidza nemakemikari, inova isina kuratidza bilirubin, iyo inowanzosarudzwa nemusiyano pakati pese uye zvakananga bilirubin.

Zvisinganzwisisiki zvinodanwa zvisingaverengeki kana kusununguka - zvakasviba, seyakasviba-mafuta, zvinongopinda nyore mumasero, zvichivhiringidza basa ravo. Ndicho chikonzero izvo zviri mu fraction iyi yebilirubin muropa pamusoro pezvakanaka kune ngozi.

Iyo enzyme iri muchimiro ichi inosunga kuropa albumin uye inopinda muchiropa, iyo inowanikwa "neutralization" uye inova isina kusvibiswa nemvura. Chikamu ichi chinonzi indirect bilirubin. Enzyme yakadaro yakanyanyiswa ne bile, asi kana chiropa chinoshanda chikavhiringidzika, muviri unogumira kurarama nebasa rekushandura pasina kuratidza bilirubin muchirongwa, uye zvarinotaura muropa zvinowedzera kupfuura zvinowanzoitika.

Kuyera kweropa kwebilirubin

Nhamba ye enzyme iri muropa serum inotsanangurwa mukutsvakurudza kwehupenyu hwechimiro pane zvimwe zvinoratidza se hemoglobin, haptoglobin, cholesterol, urea, glucose, creatinine, triglycerides, nezvimwe.

Ropa rekutsvakurudza rinotorwa chete kubva mumutsipa. Pausiku wekuongororwa iwe haugoni kunwa jisi, mukaka, kofi, tipe inonaka uye doro. 8 kusvika maawa gumi nemaviri vasati vasvika ropa rinogona kudyiwa, uye laboratori inofanira kuuya pane isina chinhu mudumbu. Iwe unogona kunwa mvura.

Ruoko rwepamusoro pehuta hunosimbiswa nefurniquet, ganda rinorapwa neine antiseptic uye nenyuchi inopindirwa mumhino, iyo iyo inotorwa ropa. Sezvo mutemo, vanhu vazhinji vanofunga kuti nzira iyi haina kunetseka kupfuura kupa ropa kubva munwe.

Mhinduro dzekudzidza

Mu laboratori, bilirubin yose inotsanangurwa mu biochemical blood test - chimiro chei enzyme inowanzova 8.5 - 20.5 μmol / L, kunyange zvazvo zviyero zvingasiyana zvishoma zvichienderana nemagetsi anoshandiswa mukudzidza. Nokudaro, rimwe laboratori rimwe nerimwe rine chimiro, uye miganhu yaro inonyatsoratidzwa mumigumisiro yekuongorora.

Saka, mamwe magwaro matsamba ekuverenga, maererano nezvinodiwa zvebilirubin muhutano weropa kusvika kusvika 22 μmol / l.

Chikamu chakajeka chinosvika ku 5.1 μmol / l, uye pane zvisingazivikanwi - kusvika ku17.1 μmol / l.

Nei bilirubin yakamutswa?

Pazuva repiri rechitatu mushure mokuberekwa kwemuviri, kuparadzwa kwakasimba kwe erythrocytes kunoitika, zvisinei, bilirubin-conjugating system (iyo inoshandura chikamu chisina kujeka che enzyme mumugwagwa wakarurama) haisati yakanyatsogadzirwa muvana vanozvarwa. Nemhaka yeizvi, vana vanokura hutano hwehupenyu - hunoenda mumasvondo 1 - 3. Asi chii chinowanzoitwa bilirubin muropa rechecheche? Icho chirevo chekukwirira kwakakura kudarika vakuru: chechitatu - zuva rechinomwe mushure mokuberekwa, 205 μmol / l ye enzyme inogadziriswa (yevana vasati vasvika - 170 μmol / l). To Vhiki yechitatu chiratidzo chacho chinoderera kune tsika dzepakati 8.5-20.5 μmol / l.

Pane zvikonzero zvakasiyana siyana zvekuwedzera huwandu hweyi bile enzyme muhukuru:

1. Nhamba yeaerythrocyte yakaparadzwa yakawedzerwa, iyo ndiyo iyo hemolytic anemia , somuenzaniso.
2. Chiropa chakavhiringidzika uye hachibatsiri nebasa rokubvisa bilirubin.
3. Kubuda kwebiro kusvika kumucheche muduku kunodedera.
4. Basa remakemikari rinoumba zvakananga bilirubin rinopwanyika.

Kana imwe yezvinetso ichi ichiitika, jaundice inotanga, umo mavara emuchengetedze, ziso uye ganda rinotaruka rinoshandura yellow.