Iyo nzira yeropa coagulation inowedzera muzvikamu zvakasiyana. Yokutanga ipromboplastin maumbirwo, yechipiri ndiyo thrombin maitiro, uye chechitatu fibrinogenesis. Nokuda kwekufamba kwechikamu chimwe nechimwe muropa kunofanira kuva anticoagulant. Kana zvinhu zvepanyama zvisikwa hazvina kukwana, zvino zvinotevedzwa - zvinodhaka zvinoshandiswa.
Zviratidzo zvekushandiswa kwema antiplatelet agents
Antiagreganty - zvinodhaka zvinokonzera kushungurudza pamusana pekuvhara ropa. Maererano neanticoincidence mechanism, ivo vakakamurwa kuva mapoka maviri:
- kururamisa chiito (heparinoids, heparin);
- indirect action (derivatives of phenylidandione uye oxicumarin).
Nhasi, kunewo ma antiplatelet agents ezera idzva - kusagadzikana. Izvo zvine simba rekudzivirira huwandu hwekugarisa kweplatelets.
Kusarudzwa kwemapoka ose ezvinodhaka kunogona kuva mumwe nomumwe kana pamwe chete. Zviratidzo zvikuru zvekushandiswa kweanticoagulants zviratidzo zvehutachiona hwehutachiona (hutachiona hwehutachiona) uye hutachiona hwehutano hwakasiyana. Murwere anorayirwa kuti atore mishonga iyi kunyange nehutachiona hwehutachiona mumakoronary artery system, sezvo iyi ndiyo imwe yenzira dzinoshanda dzekudzivirira kukuru-focal and myocardial infarction .
Contraindications kushandiswa kwe antiplatelet agents
Mazuva ano antiplatelet agents havagoni kurongerwa kana murwere ane chirwere:
- zvipfeko zvekudya (kunyange mumamiriro ezvinhu ane tsika yokubuda ropa);
- itsvo dzine zviratidzo zve hematuria;
- chiropa nechiremera chakanyanya chebasa racho.
Hazvikurudzirwi kutora mishonga yeboka iri kana pane zviratidzo zveinso kusakundikana, kukanganisa kwenhemostatic, C-naK-vitamini inoshaya uye aneurysm yemwoyo.
Iyi mishonga inogona kukonzera madhara. Zvinonyanya kuoneka pavanoshandisa anticoagulants zvakananga kana zvisingaiti. Kusiyana kwakasiyana hakuve nemigumisiro yakaipa mumuviri.
Nyaya dzakawanda dzinowanzoitwa antiplatelet agents ndezvekuti:
- zvinokonzera kugadzirisa;
- headaches;
- zvinetso zvinopisa;
- kubuda ropa kune imwe nzvimbo.
List of antiplatelet agents
Anticoagulants of direct direct inogadzirisa zvakananga zvinokonzerwa neropa coagulation mumutambo wevascular. Mucherechedzo wehutachiona nejoyi inopinza inowanikwa pakarepo uye inopedza maawa matanhatu. Nhamba ye antiplatelet vashandi veboka iri inosanganisira:
- Heparinolds;
- Heparin;
- Arvin;
- Calcium heparinate;
- Chondroitin sulfates A uye C.
Inowanzoshandiswa ndiHeparin. Inokurumidza kudzivisa kuumbwa kwe fibrin uye inodzivirira kugunun'una kweplatelets eropa.
Urongwa hwemagandanga ezvimwe zvisingaenzaniswi hunosanganisira:
- Dicoumarin;
- Cincumar;
- Nafarin;
- Neodikumarin;
- Phenylin;
- Omefin.
Dzinodzivisa ropa kuvhara muviri chete. Mhedzisiro mushure mekushanda kunoza maawa 24-72 uye inopera kusvikira mazuva anoverengeka. Ndiko kune chimba ichi kuti madhiragi eboka iri anonyanya kukodzera kurapwa kwenguva refu.
Kusiyana kwezvikamu muhutano hweva antiplatelet vanoshandisa nzvimbo inokosha. Izvo zvose kuburikidza nekuti ivo vane zvishoma zvingabatanidzwa pamabasa ekugadzira ropa. Asi panguva imwechete vanovhara kana kudzivisa kubatira-aggregation nzvimbo yeplateti. Saka, pamwe chete nemimwe mishonga uye antiplatelet agents, ivo
- Butadione;
- Papaverine ;
- Anturan;
- Indomethacin;
- Imizine;
- Carbocromene;
- Parmedin.
Zvose izvi zvisingabatanidzi pamwe nekuchenjerera zvinofanira kunyorerwa kune vanhu vakwegura uye vakwegura.