Kusvika iye zvino, gentamicin mujinisi inonzi inorwisa mabhakitiriya emabasa akawanda. Kupinda mukati memasero emabhakitiriya kuburikidza ne membrane, gentamicin inonyadzisa kusangana kweprotheni ye pathogen. Kurwisana zvikuru nePseudomonas aeruginosa, mabhakitiriya e gram-negative uye Gram-positive cocci, kusanganisira iyo inopesana nemamwe marudzi emishonga inorwisa mabhakitiriya.
Kubudiswa kusunungurwa nekugadzirwa Gentamycin
Chirwere ichi chinowanikwa nenzira yehuzoro, madonhwe eziso, poda yekugadzirira kwejairo remhinduro, mvura yejojo (gentamycin sulfate). Kuumbwa kwekupedzisira, kuwedzera kune chinhu chikuru, kunosanganisira:
- sodium metabisulfite;
- sodium hydroxide;
- sulfuric acid;
- disodium munyu.
Zviratidzo zvekushandisa Gentamycin
Chirwere cheGentamicin, chinowanzoshandiswa mune zvirwere zvakakomba. Inoshanda mukurapa kwevarwere vane hutachiona husina simba, iyo inoratidzira kune varwere vane chirwere cheshuga, leukemia, nezvimwewo.
Parenteral Gentamicin inoshandiswa mukurapa kwe:
- zvirwere zvinotapukira zvemapfupa emapfupa uye mafundo, ganda (kusanganisira kupisa kukuru uye frostbite );
- dzakaoma zvirwere zvokufema uye nhengo dze ENT;
- kuputika kwakanyanya mumugwagwa wekutsvaira uye mudumbu;
- hutachiona hwepakati yenheyo system.
Gnatamycin majoko anowanzoshandiswa muzvirwere zvemadzimai. Mukuputira maitiro muzvidzidzo zvevakadzi, mushonga unotarisirwa mukati. Kuvonga kushandiswa kwemishonga inorwisa mabhakitiriya, zvinogona kudzivirira zvinetso zvakanyanya zvechirwere, kusanganisira kuberekwa .
Mirayiridzo yekushandisa Gentamicin mu ampoules
Mushonga weGentamicin unogona kutarisirwa mumuviri wevarwere zvose zviri mukati uye zvisingatauriki. Nokuda kwekushandiswa, chirwere chimwe chete chechirwere chinoderedzwa ne 50-100 ml ye isotonic chloride solution kana imwechete ye 5% solution yeglucose. Mirayiridzo inotaura kuti chirwere chemazuva ose cheGentamicin mujairo yevanhu vakuru kusvika 3 kusvika ku5 mg pa1 kg yehutatu hwehuviri, kune vana vanopfuura makore gumi nemana anopfuura 0,8 kusvika ku 1.2 mg nekg yehutatu hwehumwe, uye ichi chikamu chakaparadzaniswa kuva 2 kusvika ku 4 doses . Nzira yekurapa mazuva manomwe kusvika kune gumi. Chiremba anopinda anogona kuita kugadzirisa kubva pakurema kwechirwere, nguva yemurwere, nezvimwe zvakadaro. Anotarisawo nguva yehutano hwekurapa, iyo, mumatambudziko akaoma, inogona kuwedzerwa.
Contraindications uye nemigumisiro yejojo Gentamycin
Kushandiswa kweGentamicin hakubvumirwi:
- nekuwedzera kwekunzwa kwemurwere kumishonga inorwisa mabhakitiriya emapoka aminoglycoside;
- kukanganisa kwepimpowo basa;
- neuritis yeropa rekuongorora;
- panguva yekuzvitakura uye lactation.
Mukurapa kweGentamicin, zviitiko zvinotevera zvakashata zvinogona kuitika:
- kushungurudza, kurutsa;
- headache;
- musimba simba;
- kunetseka;
- kanda kugadzirisa zvirwere;
- Matambudziko okuongorora;
- kurasika kweruzivo rwekuenzanisa.
Iyo mishonga inokwanisa kukonzera, saka, nehutano hwepfungwa dzinobatsira, zvipembenene zvekudzivirira zvinowanzoonekwa.
Mune zvimwe zviitiko Gentamicin inotyisa kune muviri wemurwere. Chirwere chakaipa chechirwere chiri pamagumo emagetsi anowanikwa nekushanda kwezvinhu zvinonzwa uye vestibular zvakaonekwa. Muchirevo ichi, murwere anofanira kunge ari pasi pekutungamirirwa kwachiremba, kunyanya apo inonyanya kukosha kwechiremba inorayirwa kana kuti chirwere cherapi chinowedzera. Gentamicin haina kurongedzerwa pamwe chete nemishonga inorwisa mabhakitiriya ine inephro- kana ototoxic effect. Uye kunyange zvazvo pasina zvakanyatsozivikanwa pamusoro pekubatana kwegentamicin uye injection inorowa, nyanzvi dzinokurudzirwa zvakasimba kuti dzisarega kunwa munguva yose yekurapa.