Mabasa ekuchengetedzwa mumutumbi anoita masimba ehutachiona. Iyi sarudzo inosiyanisa mapurogiramu chaiwo emapuroteni eropa - immunoglobulins yemarudzi akasiyana-siyana. Sero inonzi E inodzivirira mucous membrane kubva pakupinda kwezvinhu izvo kugadziriswa uye kugadzirisa zvinogona kuitika zvinogona kuitika.
Sei kusagadzikana kwezvirwere kunowedzera, uye zvinorevei?
Izvo zvinoshandiswa pakugadzirisa hutachiona hunoti kana muviri uchinge uchinge uchinge uchinge uchinge uchitarisana ne-stimulus in submucosal layer, immunoglobulin E inotanga kuunganidza munzvimbo yacho.Zvino kana kuisa zvinhu zvinogadzikana nema proteiniti aya, kupisa kwemukati kunowedzera sekuguma kwekusununguka kwakanyanya kwe histamines uye cytotoxic zvikamu. Somugumisiro, pane zviratidzo zvakadai sokuti:
- rhinitis;
- rash on the mucous membrane and skin over;
- bronchitis;
- asthma;
- anaphylactic shock .
Nokudaro, kana immunoglobulin E yakasimudzwa, zvinhu zvinosuruvarisa zvinopinda mumuviri uye zvinokonzera kugadzirisa, izvo zvinoputika nekuputika kwemukati, zvinotanga kukura.
Chii chinowedzera immunoglobulin E kuvanhu vakuru zvinorevei?
Sezvo mutemo, mushure memakore gumi nemaviri, kuiswa kwezvakasiyana-siyana zveprotini iri mubvunzo hakusi zvakakosha kuongororwa kwekukosha. Muvanhu vakuru, immunoglobulin yekirasi E yakawedzerwa nekuda kwekusangana nguva dzose nemuviri nemararamiro mune imwe nzvimbo yekunze, uye inofanirwa (inowanzo) tsika dzechiratidzo ichi muropa dzinobva 20 kusvika 100 IU / l. Mumamiriro ezvinhu akadaro, kunyange hutachiona hwakasimba kune rumwe rudzi rwemhando inosuruvarisa hahupi hunoita kuti kuwedzerwa kwakanyanya muhuwandu hweprotiniti isingawaniki. Kwose immunoglobulin E inogona kuwedzerwa chete kana pane zvinongororwa kusvika kune rumwe ruzhinji rwe histamines uye kusanganiswa kwayo nemaronda echirwere. Mune mamwe mamiriro ezvinhu, zvibereko zveongororo inobvumira kubvumira kuongorora chirwere chete muhafu yevarwere vakuru.
Zvakakosha kuziva kuti kuwedzera kwema immunoglobulin E kunokonzerwa nezvipembenene zvisiri izvo zvinokonzera, semuenzaniso, helminthiasis. Minorasi inoparadzanisa nhengo dzomukati dzinoparadza mucous membrane. Izvi zvinokonzera kugadzirisa kwezvirwere zvemuviri, izvo zvinosanganisira kuwedzera kwekugadzirwa kwemapuroteni masero.
Zvakare zvakatsanangurwa chirwere chinogona kukanganisa zvirwere zvinotevera:
- immunodeficiency, kunyanya congenital;
- bronchopulmonary aspergillosis;
- kusanganiswa kwechirwere chinonzi bronchial asthma ne dermatitis uye rhinitis;
- IgE-myeloma.
Mukuwedzera, kuvaka chirongwa chekutsvaga zvakakwana hazvikwanisi kuziva kuti majekiseni e-immunoglobulin epi. E. Zvimwe kuongororwa kweropa zvinodiwa kuti zviratidze zvirwere zvakasiyana-siyana zvinokonzerwa nemhando dzakasiyana-siyana (inenge 600).
Iyo yose immunoglobulin E uye zvikonzero zvechiitiko ichi zvakanyanya kuwedzerwa
Kazhinji mumigumisiro yeongororo inowanikwa zvakakosha zvakakosha zvehutachiona hwemaproteni yakagadzirirwa, kubva pa2 kusvika ku50 mamiriyoni IU / l. Zvinenge zvichinyatsozivikanwa zvinogona kusimbiswa kuti munhu ane tsvakurudzo yakadaro anorwara ne hyper-IgE-syndrome.
Ichi chirwere ndechekuberekwa kwema genetic uye inowirirana nezviratidzo zvinoratidza:
- kazhinji pneumonia;
- zvipfeko paganda uye muchembera;
- rinowedzera rhinitis nekuputika kwezeve;
- kuderedza kwemafupa epafupa, osteoporosis, kazhinji kuputsika kwemakumbo;
- kufamba kwakanyanyisa kwezvikamu zvikuru;
- scoliosis;
- sinusitis;
- kazhinji fungi ye genus Candida;
- atopic dermatitis;
- dental pathology, caries kugadziriswa;
- autoimmune diseases ;
- kuchinja kwechiso chinenge chiripo (yakadzika mumhino, mhino, kudyara kwemaziso, chiki chinopisa, chichifamba mberi).