Antimulylerov hormone anozivikanwa navanachiremba kwete kare kare, asi nerubatsiro rwake, vakadzidza kuziva zvimwe zvipingamupinyi zvehutano hwekuberekwa, vanoona zvepabonde uye kunyange kufanotaura kutanga kwekumera. Kazhinji, kuongororwa kwe AMG kunorongedzerwa ne gynecologist-endocrinologist pachikwata chekutanga chekushaya rubatsiro nerubatsiro rwekubatsira kubereka vana (IVF, insemination inogadzirwa). High antimulylerov hormone - chiratidzo chinotyisa, kutaura pamusoro pekuvapo kwezvirwere zvakakomba.
AMG mune varume nevakadzi
Antimiller's hormone (AMG) glycoprotein ine chokuita nekukura zvinhu. Izvi zvinotanga kukurudzirwa panguva yekukura kwekumbryonic: munguva yechirume - muvhiki dzema7-8, uye mumangwana vasikana - pamasvondo anenge 32-36 ekudzivirira.Ndiyo hormone inotungamirira pakuumbwa kwehutano hwehutachiona: pasi pesimba re AMG, iyo asexual embryo inobvumirana (reverse development) yeMullerian ducts - rudiments yechiratidzo chekupedzisira uye fallopian tubes. Mushure mokuberekwa kwevakomana vari mumuviri, hormone inoenderera mberi kubudiswa muhuwandu hwakawanda nemaSertoli masero, uye nekutanga kwekuyaruka muzinga we antimulylerovoy hormone yakanyanya kuderedzwa.
AMG vakadzi vanogadzira granulosa mavhiri evhaari kubva pamatatu matatu ekuzvitakura vasati vasvika kumwedzi. Mukuenzanisa nevarume, zvinyorwa zve antimulylerovaya hormone muropa revasina kusimba zvepabonde zvakanyanya kuderera, uye mushure mokutanga kwekuyaruka, uwandu hwe AMH huchiderera zvishoma nezvishoma. Nei izvi zvichiitika?
Kazhinji, mukadzi wese paanenge aberekwa ane mazai emazai, ayo, nekusvika kwekutanga kokuenda kumwedzi, zvishoma nezvishoma zvinopedzwa kusvika pakuguma. Munguva yekuenda kumwedzi, mapoka akawanda anosimbiswa kamwechete mudumbu, rimwe rawo (rinotyisa) richava mazai akakura. Pane imwe nzvimbo yekutsvaga kwemajeri masero, antimulyler hormone inobudiswa inodzora kukura kwe follicles. Masayendisiti akawana kuti uwandu hwe AMG huchinyatsobatana nehuwandu hwemai mazai. Saka, nerubatsiro rweATM, munhu anokwanisa kuenzanisa chivako chemaawa chemukadzi uye anogumira mhedziso pamusoro pekutanga kwekuenda kumwedzi.
Antimulylerov hormone inokurudzirwa - zvikonzero
Kazhinji kero ye antimulylerovoy hormone muvarume ndeye 0,49-5,98 ng / ml, pamusana pepabonde yakanakisa ichi chiratidzo chinokwana 1-2.5 ng / ml. Zvechokwadi, kune zvishoma zvishoma kubva kune zvakasikwa. Somuenzaniso, pane anti-muller hormone level kusvika kusvika 3 ng / mg, haufaniri kunetseka. Zvisinei, mune vamwe vakadzi antimulylerov hormone yakanyanya kuwedzerwa: maitiro e AGM anogona kuva 5-6, uye dzimwe nguva 9 ng / ml. Ndeipi chikonzero chezvikwangwani zvakadaro?
Vanachiremba vakawana kuti mumadzimai antimulylerov hormone kumusoro kwechimiro inosanganiswa nepopo ye polycystic ovaries, uye pamwe ne granulosa cell tumor ye ovary. Mukuwedzera, imwe AMG inogona kuratidza normogonadotropic endocrine (anovulatory) kusabereka kana kunonoka mukugadzirisa zvepabonde. AMG pamusoro pemazuva ose
Mune varume, yakawedzera antimuller hormone inotaura nezve cryptorchidism (nzvimbo yezviedzo kunze kwezvinyorwa), kunonoka mukukura kwepabonde, kukanganisa mukugadzirwa kwe androgens nezvimwe zvinetso zvekuberekwa.
Zvisinei, kwete nguva dzose AMG yakakwirira inoratidza kuvapo kwezvirwere. Dzimwe nguva mamiriro ehutano ane simba guru pamigumisiro yekudzidza: kushungurudzika, zvirwere zvakanyanya, mitambo yakasimba inogona kuchinja huwandu hwehomoni muropa. Saka, mazuva matatu isati yasarudzwa, zvakakosha kutungamirira mararamiro akatsiga, kudzivisa kusagadzikana uye kudzivisa tsika dzakaipa kana zvichibvira.