Chimwe chezvinhu zvepanyama zvebasa rinokosha remuviri wemunhu zvinopiwa nemahomoni akasiyana-siyana, ayo anogadzirwa nemafungiro emukatikati mukati.
Chii chiri ACTH?
Adrenocorticotropic hormone inonzi peptide hormone, iyo inobudiswa nehutu hwepituitary uye inotungamirira basa reAdrenal cortex. Nekudaro, grencocorticoid glands inowedzera glucocorticoid hormone uye inoisvibisa muhutachiona. Kana adrenocorticotropic hormone ichibudiswa muhuwandu hwakawanda, ropa rinowedzera mumusana wezere, uye gland inokura. Mukutaura, kana ACTH isingabhadharwi zvakakwana, inogona kuitika. Corticotropic hormone inonziwo corticotropin, uye mukurapa inoshandisa zita rakapfupiswa - ACTH.
Mabasa eAdrenocorticotropic hormone (ACTH)
Nhamba yehomoni yakachengetwa ne adrenal cortex corticotropin inotungamirirwa nemhinduro yemutemo: chiyero che corticotropin chinobudiswa nehututi chepituitary chinowedzera kana kuderera kana zvichidikanwa.
Adrenocorticotropic hormone inokanganisa kugadzirwa kwehomoni dzinotevera:
- glucocorticoids, kunyanya cortisol uye cortisone, iyo inoratidzirwa sevanopesana uye inopesana nemakemikari emakemikari;
- mahomoni ezvepabonde, izvo zvinokonzerwa nekupera uye kuberekwa;
- chikamu chekugadzira adrenaline.
Kubva pane zvataurwa pamusoro apa, tinogona kugumisa kuti adrenocorticotropic hormone inonyatsotarisirwa:
- kupikisa kwemuviri kune zvirwere;
- kugadziriswa kumamiriro matsva;
- kupona mumamiriro ezvinhu anonetsa;
- kukwanisa kubereka vana.
Nhamba ye ACTH muropa inochinja zuva rose. Iyo yakawanda yakawanda ye corticotropin inowanikwa musi wa7-8 o'clock mangwanani, uye manheru mashizha ayo anoita zvishoma nezvishoma, zvichiwisira zuva rega rega. Kuwedzerwa muviri kwakanyanya, kushungurudzika uye kukanganiswa kwehomoni kuvakadzi kunogonawo kuchinja huwandu hweAdrenocorticotropic hormone muropa. Kuwedzera kana kuderedzwa mazinga eAAC kunokanganisa kushanda kwemuviri uye kunogona kuva chiratidzo chezvirwere zvakakomba.
Kana ACTH yakakwirira
Adrenocorticotropic hormone yakakwirira muzvirwere zvakadaro:
- syndrome ectopic michina ye ACTH apo iyi hormone inotanga kubereka tumarara yakaonekwa pane imwe nhengo;
- Chirwere cheAdisonison kana kuti kuberekwa kwechirwere chedrenal gland;
- Chirwere cheItzenko-Cushing, chinoitika sechikonzero chepituitary adenoma;
- mushure mekugadzirira kupindira kwekubviswa kwezvinyorwa zvinonzi adrenal;
- paraneoplastic syndrome, umo mune chisarudzo chaicho chepituitary gland kune chirwere chinotyisa, kazhinji pane pancreas.
Uyewo, uwandu hwe ACTH hunowedzera nekushandiswa kwemimwe mishonga, somuenzaniso, insulin, amphetamine kana kuti lithiamu.
Kana ACTH inoderedzwa
Adrenocorticotropic hormone inoderedzwa mune zvinotevera zvirwere:
- kuderera kwepituitary basa ;
- kuderera kwebasa re adrenal cortex;
- apo paine ma-neoplasms e-adrenal glands;
- ane hormonal therapy, apo varwere vanotora glucocorticoids;
- zvirwere zvebronchial uye mapapu.
Inofanirawo kuonekwa kuti chiremba anogona kupa chirongwa chema serum ye ACTH kana zviratidzo zvinotevera zvichionekwa:
- kuwedzera kuneta;
- stress resistance;
- kusingaperi kuneta kwechirwere;
- hypertension.
Uyewo, chidzidzo chakafanana chinoitwa kuti chiongorore muviri wemuviri kana uchirapa mishonga yehomoni.
Usarega kusarudzwa kwechiremba kuti uite kuongororwa kweAACTH level. Nemigumisiro yaro, iwe unogona kuisa zvakanaka kuongorora panguva uye wotanga kurapa kwakakwana.