Trisomi 21 ma chromosomes haawanzoitiki. Maererano nenhamba dze data, nyaya yakadaro inoonekwa 1 nguva yekuberekwa kwema600-800. Panguva imwecheteyo, zvinoratidzirwa kuti kuwedzerwa kwekukura kwehutachiona kunokura nekuwedzera kwezera remukadzi wechikadzi.
Ndezvipi zvinokonzera kukurudzirwa kwetrisomy 21 chromosomes?
Kuti uzonzwisisa zvinorehwa ne trisomy 21 chromosomes, zvakakosha kuziva zvikonzero uye zvikamu zvehutachiona huno. Kusvikira zvino, hapana chikonzero chaicho chekuvandudzwa kwehutano. Masayendisiti akawanda anouya kumhedziso yokuti chirwere ichi chinoitika semugumisiro wekubatana kwepakati pemarudzi ega ega, ayo ekupedzisira anotungamirira pakuumbwa kwetrisomy. Muchiitiko ichi, mazita ega ega anowedzera kushanda. Somugumisiro wekucherechedza kusinganzwisisiki, kufambira mberi mberi kwezvisikwa, kunyanya kwepfungwa yepfungwa, kunovhiringidzika. Pamagenjini mazana mana anowanikwa pama 21 chromosomes, huwandu hwebasa hauna kugadziriswa, izvo zvinoita kuti zvive nyore kuziva chikonzero.
Iyo chete, zvichida, yakadzidza njodzi inokonzera kukura kwechirwere ndeyezera revabereki. Saka, panguva yekutsvakurudza, zvakawanikwa kuti mumadzimai emakore makumi maviri nemashanu mukana wekuva nemwana ane Down syndrome ndeye 1/1250, nezera remakore 35 - 1/400, uye nemakore makumi maviri nemashanu kubva kune makumi matatu ekuberekwa vana vane chirwere ichi. Panguva imwecheteyo, mukana wekuva nemwana ane chirwere ichi kuvabereki vane chirwere chimwechete icho che 100%. Zvisinei, kana mumwe mwana ane Down's syndrome akaberekerwa nevabereki vane utano, mukana wekuva nemwana wechipiri ane chirwere chakafanana ndi1%.
Ndeipi chirwere chinorwara?
Kuchengeta kusava nemafungiro uye kuitika kwetrisomy 21 chromosomes muvakadzi vane pamuviri, izvo zvinonzi kuongorora kunoitwa mumutambo wekutanga wega wega wega unocherechedza pamuviri. Panguva imwechete, uyewo wakaita tsvakurudzo kuti isabvisa trisomy yekromosomes 13 ne18. Kuita izvi, shanduro yeropa inoitwa mukati memavhiki gumi nema13 kusvika ku13. Kutora sampuli yezvinhu zvakasikwa zvinoshandiswa mune chimwe chinhu chakakosha, kuburikidza nekuvapo kwehutano kunotsanangurwa.
Nokuda kwekuongororwa kwetrisomy 21, nokuda kwechikonzero chakanaka, zviratidzo zvemaitiro, pamwe chete nezvimwe zvinhu zvakadai sezera, uremu, uwandu hwevana, kuvepo kana kusavapo kwemitemo yakaipa, nezvimwewo zvinongororwa.Zvino mushure mokunge tadzidza zvakakwana nekuverenga dambudziko rekuwedzera trisomy. Kukurukurirana zvakagadzirirwa neGynecologist.
Zvisinei, zvikamu chete zvekudzidza izvi hazvigoni kushanda sezvinonyanya kukosha zvekuongorora Down's syndrome. Migumisiro yekuongororwa inoratidzira kuti uwedzere kuongororwa kwe fetus usingashandisi nzira dzisina kukodzera. Kana pane njodzi yakakura yekudzivirira hutachiona, kupiswa kwechiriyori kunowanzoitwa, uyewo amniocentesis ane genetic kuongorora kwezvinhu zvakagadzirwa.
Ndivanaani uye kuongorora kunopiwa kupi?
- nguva yevakadzi vane pamuviri ava makore makumi matatu nemashanu uye kupfuura;
- kuvapo kuna anamnesis yezvinetso zvakakomba, pamwe nekuzvitakura zvisina kutsanangurwa;
- chromosomal pathologies, uyewo kuberekwa kwakaipa mumimba yepakutanga;
- kuvapo mumhuri yezvirwere zvinokonzerwa nemimba;
- zvakasiyana-siyana zvakapfurikidza zvirwere zvinopararira, mazaisai emhepo, uyewo kugamuchirwa mumatambo ekutanga ekudzivirira kwemishonga nematatogenic effect.