Pradaxa chirwere chiri cheboka reanticoagulant uye antithrombotic zvinodhaka. Vanoshandisa mumatope uye chirwere mumatambudziko munguva yemazuva anotevera kunyanya kudzivirira utous thromboembolism.
Kukwanisa kushandisa Pradax
Iyo inonyanya kushandisa chinhu ichi chemishonga inonzi dabigatran etexilate. Nokuda kweizvi, basa re thrombin rinodzingwa mushure mekushandisa maitiro ekugadzirira Pradax. Dabigatran etexilate inokurumidza kupinza uye inoshandurwa kuva dabigatran (inoshandurwa zvakananga thrombin inhibitor) munguva ye hydrolysis. Kubudirira kwemishonga kunoderedzwa ne20% kana uremu hwomunhu hunopfuura 120 kg, uye hunowedzera ne25% nehutatu hwemuviri pasi pemakiromita 48.
Zviratidzo zvekushandisa Pradax ndezvi:
- kudzivirira thromboembolism yemhepo;
- kudzivirira kwehutano hwakasiyana-siyana hwepromboembolism ;
- kudzivirira kwehutano hwehutano kune varwere vane fayira inouraya.
Kushandiswa kwePradax kunoratidzirwa kune vanenge vose varwere vane maitiro akadaro mushure mekuita kwemapfupa, kubvira pane ose mazuva ano majekiseni aya anonzi anonyanya kushanda. Uyezve, iyi mishonga inorayirwa mushure mokunge magwaro ekupedzisira endoprosthetics. Kugamuchirwa kwekurumidza kugadziriswa kwemuviri kunotanga kutanga maawa mana mushure mekupera kwebasa.
Contraindications kushandiswa kwe Pradaxi
Kunyange kana iwe une zviratidzo zvekushandiswa kwemishonga yaPradax, haugoni kuishandisa mukurapwa kwehutachiona hwehupenyu kune chero zvikamu zvemuropa. Usatanga kutora mishonga yacho yakakomba yeinso kusakundikana, kupesana kana kuti kunokonzerwa nekuvhiringidzika kwe homeostasis uye nekliniki kubuda ropa rinokosha.
Kupindirana kwekushandiswa kwe Pradax kunewo:
- akashaya chiropa basa;
- kushungurudzika kwepona nepfungwa;
- nyangadzi dzisina kunaka;
- kusagadzikana kwemvura;
- utachiona ulcer;
- intracerebral vascular disorders.
Hazvikurudzirwi kushandisa chirwere ichi pamwe chete ne antiplatelet agents. Iko kusanganiswa kune ngozi kune hupenyu, sezvo inonyanya kuwedzera njodzi yekubuda ropa zvinoda kusvika katatu. Kana pane uchapupu hwekushandiswa kwaPradax uye chiremba akasarudza kupa mishonga iyi, zvino zvakakosha kubvisa kudyiwa kweimwe mhando dzeanticoagulants. Hazvikurudzirwi kuita chirwere nemishonga yakadai kune varwere vasati vava nemakore gumi nemasere, sezvo pasina kliniki yemadhora pamusoro pemigumisiro yekushandiswa kwayo panguva ino iripo.