Pilocarpine inodonha ziso pane imwe nhengo yealkaloid, inowanzoshandiswa kuderedza kushanda kwepisocular uye mukurapa kwe glaucoma.
Iyo nzira yekuita kwePilocarpine inokonzerwa nekuti inokonzera kuderedzwa kwechidiary muscle uye chitenderera musumbu we iris nekuda kwechiitiko chinokurudzira M-cholinergic receptors. Izvi zvinowirirana nekuvandudzika mukati mekubuda kwemukati wehutachiona uye kuderedza mwana. Somugumisiro, zvirongwa zvemagetsi muziso maziso dzinovandudza, uye intraocular pressure inoderera.
Kuumbwa uye chimiro chekusunungurwa
Chirwere ichi chinowanikwa se 1% solution, muhombodo dzepurasitiki nemudonzvo, guru 10 kana 5 ml.
Kuumbwa kwemadonhwe eziso kunosanganisira:
- pilocarpine hydrochloride (10 mg ne 1 ml yegadziriswa, iyo inoshandiswa inoshandiswa);
- boric acid;
- mvura yejojo.
Nhengo dzePilocarpine mishonga yakadaro:
- Salazon;
- Kazhinji Pilocarpine;
- Pilocarpine-Dia;
- Pilocarpine-Long;
- Pilocarpine-Ferein.
Pilocarpine - zviratidzo zvekushandiswa
Madoncarpine madonhwe anoshandiswa mukurapa kwe:
- kurwisa kwakanyanya kwekona-kuvharwa glaucoma;
- primary and chronic open-angle glaucoma;
- ine chisingagumi yakavharwa-angle glaucoma (vasati vambovhiyiwa);
- yechipiri glaucoma, iyo yakagadziriswa semugumisiro wekushaya ropa mukati me vitreous;
- retinal vein thrombosis;
- atrophy ye optic nerve ;
- pigmentary degeneration ye retina.
Uyewo, mushonga unoshandiswa kuderedza vadzidzi vane kunyanya kudengenyeka kwemashoko, nechinangwa chokuongororwa uye munguva dzekuvhiya dzimwe nzira.
Mirayiridzo yekushandiswa kwemadonhwe eziso Pilocarpine
Kuwanda kwekushandiswa uye chiitiko chechirwere chinowanzogadzwa nachiremba.
Kazhinji kazhinji, ne-primary glaucoma, mishonga inoiswa mu 1-2 madonhwe katatu pazuva. Mukurapa kwekurwa kwakanyanya kwekona-yekuvhara glaucoma, kuwedzerwa kwekudzidzira kunoparadzaniswa kubva kamwe kamwe mumaminitsi gumi nemashanu muawa yekutanga, kusvika pamasere matatu kusvika matanhatu shure kweizvozvo, kusvikira kurwisa kwamira.
Kazhinji, madonhwe ePilocarpine anotangwa 30-40 maminitsi mushure mekushandiswa, uye zvakanyanya kuitika zvinopera mushure meawa 1.5-2. Chirwere ichi chinongopinda nyore mu-cornea uye
Kupindirana kwekushandiswa kwemadonhwe aya kunosanganisira munhu wese hypersensitivity kune chero ipi zvayo, zvirwere zvemaziso uye mashure endoperative umo kuomeswa kwevadzidzi hakusi kudiwa:
- keratitis;
- irit;
- iridocyclitis .
Kuchenjerera kunoda kushandiswa kwe pilocarpine kune varwere vane huwandu hwemyopia uye retinal detachment. Paunenge uri nepamuviri, ita kuti iyi mushonga isakurudzirwa.