Chirwere cheM Werlhof - thrombocytopenic purpura - chirwere chinoratidzwa nenzira yehemorrhagic effusions pamusoro pechirango chekuwedzera aggregation (gluing) yeplatelet. Yakagadzirirwa microthrombi yakavhara mazhenje emadetri maduku. Mukuwedzera, pane kusanganiswa kwemasero eropa uye kuderera kwechiverengero cheplatelets.
Zvinokonzera Matwere aWerlhof
Pari zvino, izvo zvinokonzera thrombocytopenic purpura hazvizivikanwi. Ipai maitiro ekutanga uye echipiri chechirwere cheVerlhof. Mafomu makuru anowanikwa nhaka mune zvechisikwa kana kuratidza sechikonzero chechirwere chepachirwere. Secondary forms ane zviratidzo zvezvirwere zvakawanda.
Zviratidzo zveVirlhof's Disease
Chirwere ichi chinotanga, nokuti hapana chikonzero chakajeka, pane dzimwe nguva kurwisana nemamiriro ekurwa kwepamuviri kana ARI. Mune murwere panguva yekutanga, zviratidzo zvinotevera zvinoratidza:
- fever;
- kushungurudzika (kunogona kurutsa);
- headache;
- kushaya simba, kunyanya;
- kurwadziwa mubhokisi uye mudumbu.
Chiratidzo chikuru ndechekuvhiringidza uye kushandiswa kwemuviri, izvo zvinotsanangura zita rechipiri chechirwere - thrombocytopenic purpura.
Mushure mechinguva chiduku, chirwere chinonzi hemorrhagic syndrome chinozviratidza zvikurukuru nenzira ye:
- manya, kubuda kwemimba, uye mumadzimaiwo uterine;
- kubuda ropa , mucous membrane;
- kuputika mukati me retina yeziso;
- hemoptysis.
Hemorrhagic zviratidzo zvinowirirana nezvinetso zvepfungwa, zvakadai se:
- kukanganisa;
- kugona;
- kunyunyutika muhara uye nguva;
- kuparara kwemaonero;
- unilateral kuparara.
Mumatambudziko akaoma, zvinokwanisika kukudziridza coma.
Hemorrhages pasi peganda yakawanda uye inogara nzvimbo huru. Zvichienderana nemishonga, zvinoshandiswa zvinoshandiswa kubva kune zvitsvuku-tsvuku kusvika kune zhizha (sekuputsika kwekare).
Kuongororwa kwechirwere chaVerlhof kunotanga nekuongororwa kwemurwere uye anamnesis. Dambudziko rekuongorora rinosanganisira miedzo inotevera:
- Kuongorora kukuru kweropa (OAK). Chirwere chacho chinotsanangurwa nekuderedza uwandu hwe erythrocytes uye hemoglobin, kuderedza nhamba yeplatelet uye kuona antiplatelet antibodies.
- Sternary kutengesa - kutora marora emapfupa ekuongororwa achishandisa sternum puncture. Muchidzidzo chekuisa masero, kuwedzera kwenhamba ye megakaryocytes, nhamba shoma yeplatelet, inowanikwa, asi pasina humwe humwe humwe hunochinja mumapfupa emafuta, somuenzaniso, iyo inofanirwa nehutachiona.
- Trepanobiopsy - chidzidzo chepfupa remapfupa ne periosteum uye bone (kubva munharaunda yepelvic), inotorwa nerubatsiro rwechipatara chimbo che trephine. Ne chirwere chaVerlhof, chiyero chemafuta uye hematopoietic bone marrow chinopindirana nechinangwa.
Kurapa kwezvirwere zveVerlhof
Zvirongwa zvekurapa zvinoenderana nedzimwe chirwere chacho. Mishonga inoitwa neimwe yenzira dzinotevera:
- Kushandiswa kwekorticosteroids nokuda kwekusunga hemorrhagic syndrome uye kuwedzera huwandu hweplatelet muropa. Prednisalon inorayirwa payero ye 1 mg pa 1 kg yehutano hwehutwere pazuva. Kana zviitiko zvakakomba zvechirwere ichi, chirwere chacho chakavirirwa.
- Kana zvakakosha zvisingagoneki, murwere anorayirwa kubvisa spleen . Maererano nehuwandu hwezvokurapa, mu80% yevarwere mushure mekuvhiyiwa kwekuvhiya kwakakwana kunoonekwa.
- Muzviitiko zvisingawanzoitiki, shure kwepleen splenectomy, kubuda ropa, uye chirwere ichi chinoramba chiripo, zvirwere zvinoshandiswa nemaviri zvinorayirwa (Azathioprine, Vincristine) uye glucocosteroids.
Kuti abvise zviratidzo zvekunze kwehemorrhagic syndrome, haemostatic agents anoshandiswa:
- Adroxon;
- Diet;
- Chipembenene cheHemostatic;
- estrogens.