AFP - chii ichocho?

Kazhinji, vakadzi, vari munzvimbo, vanopa mimwe miedzo yakawanda, inorongwa uye maererano nemurairo wechiremba, anotungamirira pamuviri. Uye kana, somuenzaniso, munhu wose anoziva zvinonzi progesterone, chii icho AFP chiri uye kuti ropa rinodururwa nokuti rinozivikanwa kune vashomanana.

Alpha-fetoprotein (AFP) inowanikwa puroteni inoberekwa zvakananga muropa uye mukati memakumbo embryo.

Ko AFP inoshanduka sei pakuberekwa?

Inoshandiswa panguva yakatarisa kuongororwa kwemarudzi akasiyana-siyana ematambudziko mu fetal stage yekukura kwe fetal. Pakutanga danho rekuvandudza, puroteni iyi inobudiswa nehutano muviri. Kutanga kutanga kubva pa5 vhiki yekutakura, fetus inotanga kuzvigadzira iri yoga. Nokudaro, alpha-fetoprotein inoita basa rekudzivirirwa kumucheche, kusina kubvira kwekurambwa kwemukomana nemuviri waamai.

Sezvo huwandu hweAAFP huri muhucheche huchiwedzera, huwandu hwayo hunowedzera muropa raamai. Nokudaro, iyo yakanakisisa yeprotheni inongopera masvondo gumi nematanhatu. Ndicho chikonzero AFP ine hutachiwana hunenge huchiripo, mukadzi ari kuzviita musi uyu. Iyo yakawanda yakanyanyogadziriswa yeprotheni iyi inosvika mavhiki 32-34, mushure mokunge inopera zvishoma nezvishoma. Saka, ne1 gore yezinga re alpha-fetoprotein mumuviri wemakungu unosvika pakukosha kwayo.

Kuongorora kweAAPP kwakagadziriswa sei?

Kazhinji, vakadzi vane pamuviri, kupa ropa ku AFP, havazivi kuti chii, uye nenzira iyo, havazive mitero yezvinodiwa. Mhedzisiro yemitemo yenyika dzakawanda mune mufambiro wekuongororwa kwakadaro iMoM (median). Inotaridzirwa nokuverenga kuenzanisira kukosha mu-pre-seted protein-level values. Munyaya iyi, pane imwe nguva yehutachiwana hunhu hwekukosha kwayo. Chimiro che AFP panguva yekuzvitakura ndiko kuchinja kwemazana emaprotheni mukati me 0.5-2.5 MoM.

Mukuda kwekuwedzera mumatongerwo e AFP pamusoro pezviitiko izvi, vanachiremba vanofunga kuti pane chirwere mu fetus kana kuputsa mumuviri wemukadzi ane pamuviri. Saka, mufananidzo wakafanana unogona kuonekwa apo:

• multiple pregnancy ;
• necrosis yechiropa;
• malformation ye neural tube ye fetus;
• pathology the anterior bdom wall;
• umbilical hernia mu fetus .

Iko kuongororwa kunoitwa pa AFP?

Mukuwedzera, kuti kuongororwa kwekutarisana nehuwandu hwe AFP huri kuitwa panguva yekuzvitakura, inogona kushandiswa kugadzirisa zvirwere mumarume uye kwete vakadzi vane pamuviri. Saka, kazhinji kana pane kusafungirwa kwevecology, nhamba yeAAFP inoita basa rekusimbisa, asi kwete vose vanopedza kuongorora vanoziva kuti chii. Saka kuwedzera kwehuwandu hweprotini iyi mumuviri kunogona kukonzerwa ne:

• kenza yechiropa, makanda, colon;
• ronda rukuru;
• chirwere chechiropa;
• acute viral hepatitis;
• chisingakoshi renal failure.

Sezvaunogona kuona, urongwa hwezvirwere huri kuongorora uku hunoitwa hwakazara.

Ndezvipi zvakajeka kupa ruoko pamusoro pekuongorora ku AFP?

Kuongorora kwe AFP pachako pachako hakudzidzisi zvakakwana. Saka, nguva dzose data yake inotsigirwa ne ultrasound. Kazhinji pakuberekwa, pamwe nekusvika kwehuwandu hwe alpha-fetoprotein, hutachiona hwemhomoni inotaridzika, inogonesa gynecologist kuti aongorore mamiriro ehutano hwemucheche. Nokudaro, kazhinji kuongororwa kunogadzirirwa kusarudza kwe chorionic gonadotropin muropa.

Kuti uite chidzidzo ichi, ropa rinobviswa kubva mumutsipa wevakadzi vane pamuviri. Panguva imwecheteyo, nguva yakakwana masvondo 14-15, asi fence inogona kuitwa mukati memavhiki 14-20 ekuzvitakura. Kufanana nemuedzo wakawanda, AFP inoshandiswa pane isina chinhu mudumbu, mangwanani. Muchiitiko ichi, mushure mekudya kwekupedzisira inofanira kutora maawa 4-6.

Nokudaro, kuongororwa kwe AFP kunobvumira kusarudzwa kwenguva yakakwana kwehutachiona husina kunaka.