Chii chinonzi vitrification uye chinoshandiswa kupi?
Iyi nzira itsva inofanana zvikuru neyogyopreservation, umo kuvhenekera kwevakadzikadzi zvepabonde masero ari kuitwa. Zvinonyanya kukosha izvi, kunyanya, munguva yeVIV, apo kutanga kwekutanga kunogona kukundikana. Kuti usasarudze zvakare maoocyte, shandisa vitrified. Cherechedza kuti maoocyte ari mavheti asina kufanana ari mukati mawo mavari.
Kubudirira kukuru kwemuitiro uyu ndeyekuti, kana ichienzaniswa ne- cryopreservation, vitrification inobvumira nguva yakareba kuchengetedza masero epabonde pasina kuderedza kushanda kwavo. Mukuwedzera, iyi nzira inowedzera inoderedza zero mikana ye oocyte kukuvara panguva yekuzununguka, uye panguva imwe chete, kubudirira kwezvirongwa zvekugadzira maitiro hazvisi kuderera.
Sezvatotaurwa pamusoro apa, nzira iyi inoshandiswa zvikuru mumitambo ye in vitro fertilization. Sezvo mutemo, vanoshandisa kwairi apo:
- kusagona kuwana spermatozoa zvakananga pazuva rokuvhara panguva yeVIV;
- hazvigoneki kuronga kubata pamuviri munguva pfupi iri mberi (kana pane zvinopesana nezvinobva pakuberekwa kana kusagutsikana mukati momukadzi pachake, somuenzaniso);
- imbere chemotherapy mune vakadzi vane kenza (kurega kukanganisa kwemakemikrasi pamasero epabonde);
- Chido chekuchengetedza maoocyte avo mushure mokunge vapera.
Ndezvipi zvakanakira nzira iyi?
Apo kuvharidzira maoocyte asina kuchena, maoocyte, kushandiswa kwemhepo kunopera munguva shoma. Pamusana peiyi ino, microscopic ice cristal, iyo inogona kukuvadza shell oocyte, haisisina nguva yekuumba. Nokudaro, mushure mekunyangarika, vanachiremba vanogona kukwira kusvika ku 98% yevakadzi vanogona kushandisa majekiseni emagetsi. Zvakakosha kuziva kuti ne cryopreservation, hapana 60% vanogara.
Kuitwa pamusoro pekubudirira kweyi nzira, zvidzidzo zvakaratidza kuti maoocyte asina kubvongodzwa anogadzirwa nemafungiro akaenzana seaya masero ari muvirikadzi. Paunenge uchiita gorofreservation, pane chimwe chinhu chakadai sekuwedzerwa kweiocyte membrane. Ichi chinokosha chinonyanya kuoma kupindira kwehuta mukati mazai.
Ndezvipi zviratidzo zvehutrification?
Nguva pfupi kusati kwatanga kuvhara mukati momuviri wemadzimai, hutachiona hwehutachiona hunoitwa hunoita kuti hunyuchi huvepo. Nenguva isati yatanga kusunungurwa kweavo kubva ku follicle, ultrasound inopiwa. Izvi zvinoita kuti zvikwanise kugadzirisa kana mazai akakura akakodzera kubhadhara. Kana zvikasakwanikwi - nzira yekukurudzira inodzokorora zvakare.
Nzira yacho inowanikwa pasi peanesthesia yakawanda. Panguva imwecheteyo, kuwanika kunowanikwa kunze kwekushandisa, uchishanda nenyuchi chaiyo. Iyo nzira inodzorwa nemichina ye ultrasound. Maoocyte akaunganidza akaoma uye anogona kuchengetwa kwenguva yakareba.
Nokudaro, zvinogona kutaurwa kuti cryopreservation uye vitrification ndiyo nzira mbiri dzakafanana, dzinoitwa nenzira imwe chete, asi dzine zvigaro zvadzo zvekuita. Munguva pfupi yapfuura, IVF ine kubwinya kwave ichiwedzerwa kushandiswa, kusanganisira nechinangwa chekugadzira bhengi reoocytes mumakiriniki ekuberekwa.